Both formulas begin with a foundation of ESC (eggshell calcium). The differences come with the additional ingredients. Calcium Mag +D is a basic calcium, magnesium and vitamin D supplement and would be a good choice for adolescents and young women - up to women in their 30’s. Bone Health Advanced also contains magnesium and Vitamin D. In addition, it provides Vitamin K2 and boron. These two ingredients provide added benefits for calcium absorption and utilization. As we age, it can become more difficult for our bodies to put calcium where it belongs - in our bones. Bone Health Advanced would be ideal for women in their 40’s, post-menopausal women and women with a strong predisposition for osteoporosis.